BMIE

BioMaterials for ImmunoEngineering (BMIE) Lab

bmie2022

Our labaratory

Biomaterials for Immuno-Engineering Lab develops biomaterials to tackle problems in immunology and immunotherapy. Balanced immunity is essential for our health, as weak immunity is susceptible for infection and tumorigenesis whereas over-activation of immunity can cause autoimmune diseases and hyper-inflammation (e.g. severe COVID-19). We develop biomaterial-based approaches to monitor and control immune system to deepen our understanding and to treat immune-related diseases. In particular, we are interested in cancer immunotherapy, a therapy to treat cancer by harnessing the power of immunity. Biomaterial-based ex vivo models recapitulating tumor-immune microenvironment (TIME) can be useful in understanding fundamental mechanisms underlying cancer immunotherapy. Biomaterial-based delivery system will allow us to deliver various therapeutics to TIME in a spatio-temporally controlled manner to maximize efficacy and minimize toxicity.

Research

Professor

Department of Materials Science and Engineering Seoul National University

1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea

E-mail: jsdoh@snu.ac.kr

EDUCATION

Ph.D. Department of Chemical Engineering / Program in Polymer Science and Technology,
Massachusetts Institute of Technology (9/2001 ~ 6/2006).

B.S. Department of Chemical Engineering, Seoul National University (3/1995 ~ 2/1999)

PROFESSIONAL CAREER

Associate Professor, Department of Materials Science and Engineering, Seoul National University (3/2019 ~ )

Visiting Associate Professor, Department of Chemical and Biomolecular Engineering, University of Pennsylvania (7/2014 ~ 3/2015)

Assistant and Associate Professor, I-Bio/Department of Mechanical Engineering, POSTECH (2/2008 ~ 2/2019)

Postdoctoral Researcher, Department of Pathology, University of California at San Francisco (9/2006 ~ 1/2008)

Postdoctoral Researcher, Department of Materials Science and Engineering, Massachusetts Institute of Technology (6/2006 ~ 8/2006)

RESEARCH AREAS

Cancer immunotherapy

Micro-engineered platforms for the study of immune cell communications

Multi-scale fluorescence imaging (two-photon, confocal, TIRF, wide-field) of molecular and cellular dynamics

PROFESSIONAL ACTIVITIES

Faculty Member of Faculty of 1000 (F1000) in Cell Adhesion & Migration (8/2014 ~ 7/2016)

Editorial board member of PLoS One (9/2014 ~ present)

Editorial advisory board member of F1000Research (12/2014 ~ present)

Member of Biomedical Engineering Society (BMES), American Association of Immunologists (AAI), American Society for Cell Biology (ASCB), and Biophysical Society (BPS)

Member of Korean Biochip Society (KBCS), Korean Society for Biomaterials (KSBM), Korean Society of Mechanical Engineers (KSME), Korean Association of Immunologists (KAI)

Reviewer of PNAS, Sci. Adv., Acc. Chem. Res., J. Am. Chem. Soc, ACS Nano, ACS Appli. Mat. Inter., Langmuir, J. Phys. Chem., Mol. Pharm., Anal. Chem., Biomaterials, Acta Biomaterialia, Biotechnology & Bioengineering, J. R. Soc. Interface, Nanoscale, Integrative Biology, Lab Chip, Biomat. Sci., Adv. Funct. Mat., Small, Adv. Healthcare Mat, Sci. Rep., Biofabrication, Sensors & Actuators: B. Chemical, Polymer International, Phys. Biol., J. Control. Release, Cancer Lett. Microsys. Nanoeng., Biosens. Bioelec.